자몽종자추출물과 차추출물 및 UDCA를 배합한 구내분무액의 S. mutans와 구취 감소효과 및 치은염완화효과에 관한 연구
Effects of mouth spray containing GFSE, tea extract & UDCA on antimicrobial effect of streptococcus mutans, reducing of oral malodor and reduction or gingivitis
소속 상세정보
1정세환/Se Hwan Jung
1배광학/1문혁수/1백대일/1김종배/2/3박덕영/Kwang Hak Bae/Hyock Soo Moon/Dai Il Park/Johng Bai Kim/Deok Young Park/Deok Young Park
KMID : 0355419980220010037
Abstract
The purposes of this study were to evaluate the elects of mouth spray containing
GFSE, tea extract and UDCA on antimicrobial effect in Streptococcus mutans, reducing
oral malodor and reduction of gingivitis. Three different mouth sprays which contained
1) 0.01% GFSE, 2) 0.01% GFSE + 0.10% tea extract, 3) 0.01% GFSE + 0.10% tea
extract + 0.02%UDCA were tested. In this cross-over antimicrobial resistance study, 30
students aging 20 to 24 participated. There were three experimental periods continued
one weeks each and two control periods between experimental periods. Colony count
number of Streptococcus mutans in 0.1% peptone garggling solution were measured.
In order to evaluate the elect of experimental mouth sprays on reducing oral malodor,
the authors had analysed the volatile sulfur compounds(VSC) in mouth odor after
chewing of 0.5mg garlic powder. Following mouth air sampling immediately after the
chewing of garlic powder, subjects used mouth spray and re-evaluated at 3,8, and 13
minutes respectively after chewing of garlic powder. Gas chromatographic technic was
employed for the evaluation of VSC in mouth air. The percent change in VSC
concentration of air samples were calculated in relation to values of mouth air sample
immediately after the chewing of garlic powder.
40 subjects completed a two weeks, double blind clinical study of experimental mouth
sprays on reduction of gingivitis. Subjects were divided by three experimental and one
control group. Gingival index were scored three times : 1) before dividing group, 2)
after one weeks, 3) after two weeks. Gingival index which modified Loe & Silness were
used to score the gingivitis.
The results obtained were as follows:
1. Mean counts of Streptococcus mutans of three experimetal mouth sprays containing
GFSE, tea extract and UDCA were significantly decreased, as compared to that of the
control mouth spray(P<0.05).
2. Three experimetal mouth sprays containing GFSE, tea extract and UDCA reduced
more methylmercaptan than control mouth spray(P<0.05).
3. The experimetal mouth spray containing 0.01% GFSE, 0.10% tea extract, and 0.02%
UDCA significantly reduced gingivitis, as compared to the control mouth spray(P<0.05).
키워드
자몽종자추출물; 차추출물; urusodesoxycholinic acid; 구내분무액; 구취감소효과; S. mutans; GFSE; tea extract; UDCA; mouth spray; oral malodor; S. mutans;
원문 및 링크아웃 정보
등재저널 정보